Avoiding cell death

Cancer_hallmark_apop

 

 

 

 

 

 

 

Cells get damaged all the time; so does their DNA.  A cell can die in one of two ways - unplanned death called necrosis, or planned death called apoptosis.  When it comes to planned death, the cell may be killed off by its neighbours who can sense that the cell has gone wrong and act to prevent it becoming a problem.  Alternatively, damaged cells can be killed by their own programming – ring any bells? ...  ‘Vital software has encountered a problem and has to close.’

Hallmark1programmeddeath.png
Cells can realise that they are damaged and shut themselves down.
Cancer_hallmark_cell
Cells can be killed off by their neighbours.
Cancer_hallmark_escape
But, cancer cells learn to escape death.

 

 

 

 

 

 

 

 

 

 

This ability to be killed off when a cell goes wrong is vital to teamwork amongst cells.  When cells learn to escape from death, a significant teamwork chapter has been damaged.